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CCDC98 Polyclonal Antibody

CAT: 0498-bs-6921R-TRSize: 20 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-6921R-TRSize:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
Synonyms
ABRA1; CCDC98; BRCA1-A complex subunit Abraxas; Coiled-coil domain-containing protein 98; Protein FAM175A; FAM175A; UNQ496/PRO1013
Gene ID
84142
Swiss Prot
Q6UWZ7
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
51-150/409
Target
CCDC98
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CCDC98
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Human, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken
Gene ID URL
84142
Isotype
IgG

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