TLR7 Polyclonal Antibody

• Background:

  Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity) .

• Synonyms:

  TLR7-like; Toll-like receptor 7; TLR7; UNQ248/PRO285

• Gene ID:

  51284

• Swiss Prot:

  Q9NYK1

• Cellular Locus:

  Cytoplasm, Cell membrane

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse

• Immunogen:

  461-560/1049

• Target:

  TLR7

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human TLR7

• Applications:

  WB, ELISA

• Purification:

  Purified by Protein A.

• Concentration:

  1ug/ul

• Dilution:

  WB (WB=1:500-2000), ELISA (ELISA=1:5000-10000)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  51284

• Isotype:

  IgG