TLR7 Polyclonal Antibody

• Background :

  Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity) .

• Synonyms :

  TLR7-like; Toll-like receptor 7; TLR7; UNQ248/PRO285

• Gene ID :

  51284

• Swiss Prot :

  Q9NYK1

• Cellular Locus :

  Cytoplasm, Cell membrane

• Host :

  Rabbit

• Cross Reactivity :

  Human, Mouse

• Immunogen :

  461-560/1049

• Target :

  TLR7

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human TLR7

• Applications :

  WB, ELISA

• Purification :

  Purified by Protein A.

• Concentration :

  1ug/ul

• Dilution :

  WB (WB=1:500-2000), ELISA (ELISA=1:5000-10000)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  51284

• Isotype :

  IgG