Products for Research Use Only
RegisterLogin

ECT2 Polyclonal Antibody

CAT: 0498-bs-4102R-TRSize: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-4102R-TRSize:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Guanine nucleotide exchange factor (GEF) that catalyzes the exchange of GDP for GTP. Promotes guanine nucleotide exchange on the Rho family members of small GTPases, like RHOA, RHOC, RAC1 and CDC42. Required for signal transduction pathways involved in the regulation of cytokinesis. Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Regulates the translocation of RHOA from the central spindle to the equatorial region. Plays a role in the control of mitotic spindle assembly; regulates the activation of CDC42 in metaphase for the process of spindle fibers attachment to kinetochores before chromosome congression. Involved in the regulation of epithelial cell polarity; participates in the formation of epithelial tight junctions in a polarity complex PARD3-PARD6-protein kinase PRKCQ-dependent manner. Plays a role in the regulation of neurite outgrowth. Inhibits phenobarbital (PB) -induced NR1I3 nuclear translocation. Stimulates the activity of RAC1 through its association with the oncogenic PARD6A-PRKCI complex in cancer cells, thereby acting to coordinately drive tumor cell proliferation and invasion. Also stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
Synonyms
ARHGEF31; Protein ECT2; Epithelial cell-transforming sequence 2 oncogene; ECT2
Gene ID
1894
Swiss Prot
Q9H8V3
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
781-883/914
Target
ECT2
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ECT2
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse, Dog, Cow, Chicken, Rabbit
Gene ID URL
1894
Isotype
IgG

Related Products

CatalogName
bs-5344RPhospho-ECT2 (Thr373) Polyclonal Antibody
bsm-51635MECT2 Monoclonal Antibody
bs-5344R-BiotinPhospho-ECT2 (Thr373) Polyclonal Antibody, Biotin Conjugated
bs-5344R-RBITCPhospho-ECT2 (Thr373) Polyclonal Antibody, RBITC Conjugated
bs-5344R-PerCPPhospho-ECT2 (Thr373) Polyclonal Antibody, PerCP Conjugated
bs-5344R-PEPhospho-ECT2 (Thr373) Polyclonal Antibody, PE Conjugated
bs-5344R-HRPPhospho-ECT2 (Thr373) Polyclonal Antibody, HRP Conjugated
bs-5344R-FITCPhospho-ECT2 (Thr373) Polyclonal Antibody, FITC Conjugated
bs-5344R-Cy5Phospho-ECT2 (Thr373) Polyclonal Antibody, Cy5 Conjugated
bs-5344R-Cy3Phospho-ECT2 (Thr373) Polyclonal Antibody, Cy3 Conjugated

Alternative Products

CatalogName
RD253424A-01ECT2 Polyclonal Antibody
NBP2-68630Rabbit Polyclonal ECT2 Antibody
TA371771ECT2 Rabbit Polyclonal Antibody
HV384014-01Anti-ECT2 Polyclonal Antibody
abx457127-01Protein ECT2 (ECT2) Antibody

Popular Products