PDE5A Polyclonal Antibody

• Background :

  Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:9714779, PubMed:15489334) . Specifically regulates nitric-oxide-generated cGMP (PubMed:15489334) .

• Synonyms :

  CN5A; PDE5; CGB-PDE; cGMP-specific 3',5'-cyclic phosphodiesterase; cGMP-binding cGMP-specific phosphodiesterase; PDE5A

• Gene ID :

  8654

• Swiss Prot :

  O76074

• Cellular Locus :

  Cytoplasm

• Host :

  Rabbit

• Cross Reactivity :

  Human, Rat

• Immunogen :

  101-200/875

• Target :

  PDE5A

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human PDE5A

• Applications :

  WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

• Purification :

  Purified by Protein A.

• Concentration :

  1ug/ul

• Dilution :

  WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Prediction Reactivity :

  Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit, GuineaPig

• Gene ID URL :

  8654

• Isotype :

  IgG