GLK Polyclonal Antibody

• Background :

  Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.

• Synonyms :

  GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-4; Hexokinase-D; GCK

• Gene ID :

  2645

• Swiss Prot :

  P35557

• Cellular Locus :

  Cytoplasm, Nucleus

• Host :

  Rabbit

• Cross Reactivity :

  Human, Rat

• Immunogen :

  101-200/465

• Target :

  GLK

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human GCK

• Applications :

  WB, ELISA, FCM, IHC-P

• Purification :

  Purified by Protein A.

• Concentration :

  1ug/ul

• Dilution :

  WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

• Prediction Reactivity :

  Mouse, Dog, Pig, Horse, Chicken, Rabbit

• Gene ID URL :

  2645

• Isotype :

  IgG