APC-Labeled Mouse H-2Db&B2M&TRP1 (TAPDNLGYA) Tetramer Protein

APC-Labeled Mouse H-2Db&B2M&TRP1 (TAPDNLGYA) Tetramer Protein

• Background: TRP1 refers to tyrosinase-related protein. TRP1 is encoded by the TYRP1 gene. It is the human homologue of the brown (b)-locus in mice, the corresponding protein of which is associated with melanogenesis and pigmentation disorders of the skin. The exact function of TRP1 is still unknown. Besides its enzymatic activity, it may also play a structural role in the melanosome. TYRP1 is involved in the production of eumelanin, but it has also been implicated in the maintenance of the ultrastructure of melanosomes, melanocyte proliferation, and apoptosis. Defects in TYRP1 are the cause of albinism oculocutaneous type 3 (OCA3).
• Description: APC-Labeled Mouse H-2Db&B2M&TRP1 (TAPDNLGYA) Tetramer Protein (H2P-HA2H7) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Val 309 (H-2Db) & Ile 21 - Met 119 (B2M) & TAPDNLGYA peptide (Accession # P01899 (H-2Db) & P01887 (B2M) & TAPDNLGYA).
• Specifications: APC-Labeled Mouse H-2Db&B2M&TRP1 (TAPDNLGYA) Tetramer Protein is assembled by biotinylated monomer and APC-labeled streptavidin. Biotinylated Mouse H-2Db&B2M&TRP1 (TAPDNLGYA) Complex Protein is produced by co-expression of H-2Db and B2M loaded with TRP1 peptide. Biotinylated Mouse H-2Db&B2M&TRP1 (TAPDNLGYA) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
• Expression Region: Gly 25 - Val 309 (H-2Db) & Ile 21 - Met 119 (B2M) & TAPDNLGYA peptide
• Host: HEK 293
• Target: H-2Db & B2M & TRP1 (TAPDNLGYA)
• Conjugation: APC Labeled
• Tag: C-10×His
• Source: Mouse
• Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Endotoxin: 1.0 EU per μg
• Bioactivity: Immobilized APC-Labeled Mouse H-2Db&B2M&TRP1 (TAPDNLGYA) Tetramer Protein (Cat. No. H2P-HA2H7) at 1 μg/mL (100 μL/well) can bind H-2Kb/H2D Monoclonal Antibody (5041.16.1) Biotin with a linear range of 1-16 ng/mL (Routinely tested).
• Format: Powder
• Buffer: PBS, 1% BSA, pH7.4
• Additives: Trehalose
• Molecular Weight: 40.1 kDa and 15.7 kDa
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, aviod light