CD177 Polyclonal Antibody

• Background :

  Cd177 (NP1), a glycosyl phosphatidylinositol (GPI) linked N glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia and analyses showed cell surface expression of a 60 kDa protein, 14 kDa greater than the predicted size, probably due to the presence of 3 potential N glycosylation sites. Immunohistochemistry demonstrated expression in bone marrow early erythroblasts, megakaryocytes, promyelocytes, and myelocytes. The neutrophil NB1 antigen (CD177) is expressed by 97% of the caucasian population. against NB1 can be involved in neonatal alloimmune neutropenia (NAN) .

• Synonyms :

  NB1 GP; PRV-1; HNA-2a; NB1 glycoprotein; Neutrophil Glycoprotein NB1; RGD1562941; CD177 antigen; Polycythemia rubra vera protein 1; PRV-1; NB1 glycoprotein; NB1 GP; Human neutrophil alloantigen 2a; HNA-2a; CD177; CD177_HUMAN; CD177_MOUSE.

• Gene ID :

  499099

• Swiss Prot :

  D3ZCH9

• Cellular Locus :

  Cell membrane

• Host :

  Rabbit

• Cross Reactivity :

  Mouse, Rat

• Immunogen :

  521-650/818

• Target :

  CD177/NB1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from rat CD177

• Applications :

  WB, IHC-P

• Purification :

  Purified by Protein A.

• Concentration :

  1ug/ul

• Dilution :

  WB (1:300-5000), IHC-P (1:200-400)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  499099

• Isotype :

  IgG