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Lutein

CAT: 0804-HY-N6947-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N6947-01Size:5 mg
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Description
Lutein (Xanthophyll) is a carotenoid with reported anti-inflammatory properties. A large body of evidence shows that lutein has several beneficial effects, especially on eye health[1]. Lutein exerts its biological activities, including anti-inflammation, anti-oxidase and anti-apoptosis, through effects on reactive oxygen species (ROS) [2][3]. Lutein is able to arrive in the brain and shows antidepressant-like and neuroprotective effects. Lutein is orally active[4].
CAS Number
[127-40-2]
Product Name Alternative
Xanthophyll
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Apoptosis; Endogenous Metabolite; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lutein.html
Purity
90.0
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC(/C=C/[C@@H](C(C)=C[C@H](O)C1)C1(C)C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C(C(C)(C[C@H](O)C2)C)=C2C
Molecular Formula
C40H56O2
Molecular Weight
568.87
Precautions
H315, H319, H335
References & Citations
[1]Buscemi S, et al. The Effect of Lutein on Eye and Extra-Eye Health.Nutrients. 2018 Sep 18;10 (9) . pii: E1321.|[2]Kim SR, et al. Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin. Exp Eye Res. 2006 May;82 (5) :828-39.|[3]Tan D, et al. Lutein protects against severe traumatic brain injury through anti‑inflammation and antioxidative effects via ICAM‑1/Nrf‑2. Mol Med Rep. 2017 Oct;16 (4) :4235-4240.|[4]Zeni ALB, et al. Lutein prevents corticosterone-induced depressive-like behavior in mice with the involvement of antioxidant and neuroprotective activities. Pharmacol Biochem Behav. 2019 Apr;179:63-72.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Phase 4

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