ATF3 Polyclonal Antibody

• Background :

  This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.

• Synonyms :

  Cyclic AMP-dependent transcription factor ATF-3; cAMP-dependent transcription factor ATF-3; Activating transcription factor 3; ATF3

• Gene ID :

  467

• Swiss Prot :

  P18847

• Cellular Locus :

  Nucleus

• Host :

  Rabbit

• Cross Reactivity :

  Human, Mouse, Rat

• Immunogen :

  51-150/181

• Target :

  ATF3

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Source :

  KLH conjugated synthetic peptide derived from human ATF3

• Applications :

  WB, ELISA, IHC-P, IHC-F, IF

• Purification :

  Purified by Protein A.

• Concentration :

  1ug/ul

• Dilution :

  WB (WB=1:500-2000), ELISA (ELISA=1:5000-10000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:100-500)

• Buffer :

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL :

  467

• Isotype :

  IgG