HSP70 Polyclonal Antibody

• Background:

  In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.

• Synonyms:

  HSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A; HEL-S-103; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2; HSPA1A; HSX70

• Gene ID:

  3303

• Swiss Prot:

  P08107

• Cellular Locus:

  Cytoplasm

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat, Pig, Chicken

• Immunogen:

  500-600/641

• Target:

  HSP70

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human HSP70 1A/1B

• Applications:

  WB, IHC-P, IHC-F, IF, Flow-Cyt, ICC/IF

• Purification:

  Purified by Protein A.

• Concentration:

  1ug/ul

• Dilution:

  WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF (), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)

• Buffer:

  0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

• Prediction Reactivity:

  Cow, Sheep, Rabbit

• Gene ID URL:

  3303

• Isotype:

  IgG