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Recombinant human PTPRJ protein

CAT: 0498-bs-42439P-01Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0498-bs-42439P-01Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Gene ID
5795
Swiss Prot
Q12913
Expression System
E.coli
Conjugation
Unconjugated
Tag
N-His
Source
Recombinant human PTPRJ protein is expressed in E.coli with N-His. It contains the amino acid sequence of 997-1337/1337
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
20mM Tris-Hcl (pH=8.0) with 8M Urea.
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Others
Gene ID URL
5795

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