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Recombinant mouse ABCB11 protein

CAT: 0498-bs-42133P-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0498-bs-42133P-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extra- and intracellular membranes through the energy of ATP hydrolysis. ABC genes comprise seven subfamilies, designated ABC1, Mdr/TAP, MRP, ALD, OABP, GCN20 and White. The secretion of bile salt molecules from blood into bile is a major driving force for bile formation. Bile salt export pump (BSEP) is a member of the Mdr/TAP subfamily of ABC transporters that mediates the transport of bile acids across the hepatocyte canalicular membrane and regulates bile acid-dependent bile secretion. BSEP contains putative phosphorylation sites for protein kinase A, protein kinase C (PKC) and Ca2+-calmodulin dependent kinase II, whose regulation may be dependent on bile salt concentration.
Gene ID
8647
Swiss Prot
Q9QY30
Expression System
E.coli
Conjugation
Unconjugated
Tag
N-His
Source
Recombinant mouse ABCB11 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 616-750/1321
Applications
Others
Endotoxin
Not Tested
Purity
> 90% as determined by SDS- PAGE
Buffer
0.01M TBS (pH7.4)
Storage Conditions
The product should be stored at -70°C or -20°C.
Species
Others
Gene ID URL
8647

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