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Con A

CAT: 0498-bs-42101PSize: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-42101PSize:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.
Expression System
Native protein
Conjugation
Unconjugated
Source
Purified native protein
Applications
Others
Endotoxin
Not Tested
Purity
≥95% as determined by SDS-PAGE
Buffer
Lyophilized
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

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