KLH

CAT: 0498-bs-2225PSize: 10 mgDry Ice: NoHazardous: No
CAT#:0498-bs-2225PSize:10 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Keyhole limpet hemocyanin (KLH) is used extensively as a carrier protein in the production of antibodies for research, biotechnology and therapeutic applications. Haptens are substances with a low molecular weight such as peptides, small proteins and drug molecules that are generally not immunogenic and require the aid of a carrier protein to stimulate a response from the immune system in the form of antibody production. KLH is the most widely employed carrier protein for this purpose. KLH is an effective carrier protein for several reasons. Its large size and numerous epitopes generate a substantial immune response, and abundance of lysine residues for coupling haptens allows a high hapten:carrier protein ratio, increasing the likelihood of generating hapten-specific antibodies. In addition, because KLH is derived from the limpet, a gastropod, it is phylogenetically distant from mammalian proteins, thus reducing false positives in immunologically-based research techniques in mammalian model organisms. KLH can also be a challenging molecule to work with because of its propensity to aggregate and precipitate. Aggregates remain immunogenic, but limit the ability to conjugate haptens, and are difficult to manipulate in the laboratory. A high-quality KLH preparation with clear opalescent blue color is the best indicator of KLH solubility.
Expression System
Native protein
Conjugation
Unconjugated
Source
Purified native protein
Endotoxin
Not Tested
Purity
≥85% by biuret
Buffer
Lyophilized
Storage Conditions
Store at 2-8°C

Related Products

CatalogName

Alternative Products

CatalogName
MBS6232541-01DNAJC7 (DnaJ Homolog Subfamily C Member 7, Tetratricopeptide Repeat Protein 2, TPR rEpeat Protein 2, TPR2, TTC2) (MaxLight 750)
MBS6233371-01IFIT3 (Interferon-induced Protein with Tetratricopeptide Repeats 3, IFIT-3, CIG49, ISG-60, Interferon-induced 60kD Protein, IFI-60K, Interferon-induced Protein with Tetratricopeptide Repeats 4, IFIT-4, Retinoic Acid-induced Gene G-Protein, P60, RIG-G, CIG
MBS6235285-01SGTA (Small Glutamine-rich Tetratricopeptide Repeat-containing Protein alpha, Alpha-SGT, Vpu-binding protein, UBP, SGT, SGT1) (MaxLight 750)
MBS6235917-01TSPAN1 (Tetraspanin-1, Tetraspan NET-1, Tetraspanin TM4-C) (MaxLight 750)
MBS6235920-01TSPAN8 (Tetraspanin-8, Tspan-8, Transmembrane 4 Superfamily Member 3, TM4SF3, Tumor-associated Antigen CO-029) (MaxLight 750)
MBS6241195-01TSPAN2 (Tetraspanin 2, 6330415F13Rik, FLJ12082, TSN2, TSPAN-2) (MaxLight 750)
MBS6241196-01TSPAN32 (Tetraspanin 32, FLJ17158, FLJ97586, MGC22455, PHEMX, PHMX, TSSC6) (MaxLight 750)
MBS6247488-01CD151 (CD151 Antigen, CD151 Molecule, GP27, Membrane Glycoprotein SFA1, MER2, Platelet Endothelial Tetraspan Antigen 3, PETA 3, PETA-3, RAPH, SFA 1, SFA1, SFA-1, Tetraspanin-24, TSPAN-24) (AP)
MBS6249514-01CD151 (CD151 Antigen, CD151 Molecule, GP27, Membrane Glycoprotein SFA1, MER2, Platelet Endothelial Tetraspan Antigen 3, PETA 3, PETA-3, RAPH, SFA 1, SFA1, SFA-1, Tetraspanin-24, TSPAN-24) (FITC)
MBS6252216-01Tetrahydrocannabinol (THC) (PE)

Popular Products