PAK2 Recombinant Antibody

• Background:

  Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation.Acts as a downstream effector of the small GTPases CDC42 and RAC1.Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues.

• Synonyms:

  CB422; Gamma PAK; hPAK65; p27; p34; p58; p65PAK; PAK-2p34; Pak2; PAK65; PAKgamma; S6 H4 kinase.

• Gene ID:

  5062

• Swiss Prot:

  Q13177

• Cellular Locus:

  Cytoplasm

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Target:

  PAK2

• Clonality:

  Recombinant

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  KLH conjugated synthetic peptide derived from human PAK2

• Applications:

  WB, IHC-P, IHC-F, IF, Flow-Cyt, ICC/IF

• Purification:

  Purified by Protein A.

• Concentration:

  Lot dependent

• Dilution:

  WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF (), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)

• Buffer:

  0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  5062