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Linoleoyl ethanolamide

CAT: 0804-HY-113421Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113421Size:5 mg
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Description
Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1 (CB1) and CB2 receptors, and inhibits the binding of [3H]CP-55,940 with Kis of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time[1][2].
CAS Number
68171-52-8
Product Name Alternative
Linoleic acid monoethanolamide
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/linoleoyl-ethanolamide.html
Purity
99.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCC/C=C\C/C=C\CCCCCCCC(NCCO)=O
Molecular Formula
C20H37NO2
Molecular Weight
323.51
Precautions
H225, H319
References & Citations
[1]Wang X, et al. X. Synthesis of linoleoyl ethanolamide. J Oleo Sci. 2013;62 (6) :427-433. |[2]Lin S, et al. Novel analogues of arachidonylethanolamide (anandamide) : affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability. J Med Chem. 1998;41 (27) :5353-5361.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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