DUSP6 Recombinant Antibody

• Background:

  Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:9858808) . Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity) . Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain (By similarity) .

• Synonyms:

  Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3

• Gene ID:

  1848

• Swiss Prot:

  Q16828

• Cellular Locus:

  Cytoplasm

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse, Rat

• Target:

  DUSP6

• Clonality:

  Recombinant

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Source:

  Recombinant protein within Human DUSP6 aa 1-350

• Applications:

  WB, IHC-P, IHC-F, IF, Flow-Cyt, ICC/IF

• Purification:

  Purified by Protein A.

• Concentration:

  Lot dependent

• Dilution:

  WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF (), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)

• Buffer:

  0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

• Modification:

  Unmodified

• Storage Conditions:

  Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

• Gene ID URL:

  1848