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Glembatumumab vedotin

CAT: 0957-D4054-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-D4054-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Glembatumumab vedotin (CDX-011 (DOX), CR011, CR011-vcMMAE) is an antibody-drug conjugate (ADC) composed of an fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB), conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Glembatumumab vedotin has the potential for use in research of Breast cancer (TNBC) and advanced or metastatic melanoma.
CAS Number
1359940-55-8
Synonyms
CDX-011 (DOX), CR011, CR011-vcMMAE
Target
Others
Activity
Others
Storage Conditions
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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