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Mouse FDPS Ready-To-Use IHC Kit

CAT: 0498-IHC0305MSize: 50 TestsDry Ice: NoHazardous: No
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CAT#:0498-IHC0305MSize:50 Tests
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes. 1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.
Synonyms
KIAA1293, FDPS, FPPS, FPS, POROK9, farnesyl diphosphate synthase.
Cross Reactivity
Mouse
Target
Mouse FDPS
Sample Type
FFPE tissue
Components
PBS Buffer (powder) Antigen Retrieval Buffer Endogenous Peroxidase Blocking Buffer Blocking Buffer Primary Antibody Secondary Antibody Chromogen Component A Chromogen Component B Counter Staining Reagent Differentiation Reagent Mounting Media Control slide Datasheet
Storage Conditions
Storage and Stability: Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.

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