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CD107b Antibody (FITC)

CAT: 0013-GTR17857440Size: 100 TestsDry Ice: NoHazardous: No
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CAT#:0013-GTR17857440Size:100 Tests
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal antibody conjugated to FITC which recognizes CD107b that is also known as LAMP2, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 is expressed in the membranes of intracellular granules that contain effector molecules such as perforin, granzymes, eicosanoids, and histamine. It may function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion.
Product Name Alternative
LAMP-2, LAMPB
UniProt
P13473
Reactivity
Human
Immunogen
Human PBMC
Target
CD107b
Clonality
Monoclonal
Clone
H4B4
Conjugation
FITC
Field of Research
Cell Biology
Purification
Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Notes
For research use only.
Applications Notes
Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular and extracellular staining.
Tested Applications
FC
Preservative
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Isotype
Mouse IgG1 kappa
Entrez
3920

UniProtKB · P13473

Lysosome-associated membrane glycoprotein 2

LAMP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P13473
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LAMP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
LAMP-2, Lysosome-associated membrane protein 2
EC number
—
Processing
Precursor
Secondary accessions
A8K4X5, D3DTF0, Q16641, Q6Q3G8, Q96J30, Q99534, Q9UD93
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Autophagy

Cellular component

Cell membraneCytoplasmic vesicleEndosomeLysosomeMembrane

Disease

Disease variantGlycogen storage disease

PTM

Disulfide bondGlycoprotein

Domain

SignalTransmembraneTransmembrane helix

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