Products for Research Use Only

CD61 Antibody (FITC)

CAT: 0013-GTR17857426Size: 100 TestsDry Ice: NoHazardous: No
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CAT#:0013-GTR17857426Size:100 Tests
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Description
Mouse monoclonal antibody conjugated to FITC which recognizes CD61 that is also known as integrin beta-3, belongs to the integrin protein family that participates in cell adhesion and cell-surface mediated signalling by forming heterodimers of alpha and beta integrin chains. CD61 is expressed by activated T cells, granulocytes, and platelet. The CD61 antibody specifically recognizes the integrin beta3-chain of both heterodimeric complexes.
Product Name Alternative
Integrin beta 3, ITGB3, GP3A
UniProt
P05106
Reactivity
Human, Primate
Target
CD61
Clonality
Monoclonal
Clone
VIPL2
Conjugation
FITC
Field of Research
Neuroscience; Immunology & Inflammation
Purification
Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Notes
For research use only.
Applications Notes
Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Tested Applications
FC
Preservative
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Isotype
Mouse IgG1 kappa
Entrez
3690

UniProtKB · P05106

Integrin beta-3

ITB3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05106
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITGB3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A0PJW2, D3DXJ8, O15495, Q12806, Q13413, Q14648, Q16499
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumMagnesiumMetal-binding

Biological process

Cell adhesionHost-virus interaction

Cellular component

Cell junctionCell membraneCell projectionMembranePostsynaptic cell membraneSynapse

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Host cell receptor for virus entryIntegrinReceptor