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MZ1

CAT: 0498-bs-83830C-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83830C-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MZ1 consists of JQ1 tethered to a ligand for the E3 ubiquitin ligase VHL and is a selective degrader of the BET bromodomain protein BRD4. It rapidly and potently induces reversible, long-lasting and unexpectedly selective degradation of BRD4 over BRD2 and BRD3.1 It exerts anticancer effects in acute myeloid leukemia by targeting c-Myc and ANP32B.2 An important tool for studying the effects of BRD4 degradation in cancer therapy.3
Conjugation
Unconjugated
Buffer
Pale-yellow solid
Storage Conditions
-20°C

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