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Sotrastaurin

CAT: 0498-bs-83765C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83765C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sotrastaurin is a highly selective and potent (IC50’s for PKC isotypes: α = 2.1 nM, ß1 = 2.0 nM, δ = 1.3 nM, ε = 6.2 nM, η = 6.1 nM, Θ = 1.0 nM) pan-PKC inhibitor.1 Potent immunomodulatory agent that inhibits early T-cell activation and displays potential for the prevention of transplant rejection and the treatment of inflammatory diseases.2,3 Sotrastaurin has anticancer activity in various cancer models including breast4, CLL5, ocular melanoma6, and B-cell lymphoma7.
Conjugation
Unconjugated
Buffer
Orange solid
Storage Conditions
-20°C

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