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ARV-110

CAT: 0498-bs-83711C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83711C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ARV-110 is a CRBN-based PROTAC protein degrader that recruits the cereblon-containing E3 ubiquitin ligase to direct the proteasomal degradation of the androgen receptor (AR) . It selectively degrades wild-type AR and most clinically relevant mutants with low nM potency.1 ARV-110 is the first PROTAC to enter the clinic.2 Analytical methods suitable for pharmacokinetic studies have been developed.3
Conjugation
Unconjugated
Buffer
Pale yellow solid
Storage Conditions
-20°C

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