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CaCCinh-A01

CAT: 0498-bs-83588C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83588C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CaCCInh-A01 is a potent inhibitor of TMEM16A (IC50 = 2.1 mM), a calcium-activated chloride channel1. Blockade of TMEM16A with CaCCInh-A01 protects against renal fibrosis2, reduces blood brain barrier permeability, attenuates brain infarct size and neurological deficits after ischemic stroke3, and induces apoptosis and cell cycle arrest in various epithelium-originated cancer cells4.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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