Atazanavir

• Background :

  An azapeptide-based inhibitor of HIV protease (Ki = 2.66 nM) .1 Inhibits SARS-CoV-2 main protease (Ki = 703 nM), but not papain-like protease (Ki = 9.87 µM) .2 Blocks SARS-CoV-2 replication and IL-6 / TNFα production in vitro.3 Also inhibits the liver enzyme UDP-glucuronyltransferase 1A1 (UGT1A1), IC50 = 160 nM for recombinant UGT1A1.4

• Conjugation :

  Unconjugated

• Buffer :

  White to off-white solid

• Storage Conditions :

  -20°C