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TPCA-1

CAT: 0498-bs-83442C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83442C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Selective inhibitor of IκB kinase 2 (IKK2) (IC50 = 17.9 nM) .1 Inhibits production of pro-inflammatory cytokines in arthritis and other animal models of inflammation.1,2 Also attenuates NLRP3 inflammasome activation in THP-1 myeloid cells, and suppresses IL1β-induced proliferation, migration, and invasion of HeLa cells.3,4 Continuous exposure to TPCA-1 promotes expansion of hematopoietic stem/progenitor cells (HSPCs) via improved glycolysis and limited ROS production.5
Conjugation
Unconjugated
Buffer
Pale yellow solid
Storage Conditions
-20°C

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Alternative Products

CatalogName
A4602-5.1TPCA-1

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