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KNK437

CAT: 0498-bs-83441C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83441C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Inhibits constitutive and inducible HSP70 expression in non-stressed1 and heat-stressed2 cancer cells. Blocks the geldanamycin-induced induction of HSP70 and inhibition of TGFß signaling.3 Inhibits leukocyte integrin α4ß7-mediated adhesion of T cells to mucosal addressin cell adhesion molecule 1 (MAdCAM-1) suggesting that HSP70 is essential for ß7 integrin signalling.4 Suppresses morphine analgesic tolerance in a rodent model (100 mg/Kg) .5
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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B5848-10KNK437
A14389-50KNK437 50mg
A14389-100KNK437 100mg
A14389-10KNK437 10mg
A14389-5KNK437 5mg
HY-100110RKNK437 (Standard)
A14389-200KNK437 200mg
A14389-25KNK437 25mg

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