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Ascochlorin

CAT: 0498-bs-83434C-01Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0498-bs-83434C-01Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Ascochlorin is a novel isoprenoid phenol isolated from Acremonium egyptiacum and other species.1 It is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex (mitochondrial respiratory chain complex III) acting at both active sites.2 It induces caspase-independent necroptosis in LPS-stimulated RAW 264.7 macrophages3 resulting in anti-inflammatory effects4. Demonstrates substantial antineoplastic effects in a variety of tumor cell lines and mouse models.5
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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