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UK-5099

CAT: 0498-bs-83410C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83410C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent inhibitor of the mitochondrial pyruvate carrier (MPC) .1 Rapidly increases glucose uptake in human monocytes.2 Attenuates mitochondrial oxidative phosphorylation and increases glycolysis creating greater stem-like properties in LnCap prostate cancer cells.3 Blocks the neuroprotective action of L-lactate or pyruvate during glutamate-induced excitotoxicity.4 Inhibits pyruvate transport across the plasma membrane of trypanosomes (Ki=49 μM) .5
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

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