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PCI-34051

CAT: 0498-bs-83357C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83357C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PCI-34051 is a potent and selective HDAC8 inhibitor (IC50=10 nM) with greater than 200-fold selectivity over HDACs 1, 2, 3, 6, 10.1 Unlike broad-spectrum HDAC inhibitors, it does not cause detectable histone or tubulin acetylation.1 Studies employing PCI-34051 showed that HDAC8 catalyzes the hydrolysis of long chain fatty acyl lysine.2 It is a very useful tool for exploring the role of HDAC8 in cellular function.3-6
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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