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Nintedanib

CAT: 0498-bs-83353C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83353C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Nintedanib is a potent inhibitor of VEGFR, PDGFR, FGFR (IC50 = 13-34 nM for VEGFR, 59-65 nM for PDGFR and 37-108 nM for FGFR subtypes) .1 Also inhibits Flt-3, Lck, Lyn and Src (IC50 = 16-156 nM) . Inhibits VEGF-stimulated proliferation of HUVECs.1 Inhibits tumor growth in a mouse tumor xenograft model.1 A novel therapeutic agent for treatment of idiopathic pulmonary fibrosis.2,3 Alleviates chronic pancreatitis by inhibiting the activation of pancreatic stellate cells.4
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

Alternative Products

CatalogName
FM34144-01Nintedanib
C6370-5Nintedanib esylate

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