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Obeticholic acid

CAT: 0498-bs-83338C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83338C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM) . Displays anticholeretic activity in a rat model of cholestasis.1 Promotes adipocyte differentiation and regulates adipose cell function.2 Normalizes insulin sensitivity in a rabbit model of metabolic syndrome.3 A potentially new therapeutic agent for management of non-alcoholic fatty liver disease4 and NASH5. Displays therapeutic benefit in patients with primary biliary cirrhosis.6 Active in vivo.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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B1898-5Obeticholic Acid
T13092-01Tauro-Obeticholic acid
RM-O022019-01Obeticholic Acid-D5
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A13866-500Obeticholic Acid 500mg
A13866-25Obeticholic Acid 25mg
A13866-10Obeticholic Acid 10mg

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