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Blebbistatin

CAT: 0498-bs-83337C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83337C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Blebbistatin is a potent, selective, reversible, cell-permeable inhibitor of non-muscle myosin II (IC50 ~4 mM) .1,2 During cell division it inhibits contraction of the cleavage furrow without disrupting mitosis.1 Blocks cell blebbing (hence its name) and rapidly disrupts directed cell migration and cytokinesis in many cell types.1 It promotes neurite outgrowth3 and is neuroprotective against vincristine-induced neurotoxicity in iPSC-derived neurons4.
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

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