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Crizotinib

CAT: 0498-bs-83321C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83321C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A potent and selective inhibitor of c-MET and ALK, IC50s=8 and 20 nM respectively.1 Inhibition of cell proliferation was associated with G1-S phase cell cycle arrest and induction of apoptosis in ALK-positive ALCL cells (IC50=30 nM) but not in ALK-negative lymphoma cells.1 Exhibits cytoreductive antitumor efficacy via antiproliferative and antiangiogenic mechanisms.2 Clinically useful anticancer agent.3
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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CatalogName
T1661-01Crizotinib

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