Products for Research Use Only

Honokiol

CAT: 0498-bs-83286C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83286C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Honokiol is a natural product that acts as a SIRT3 activator. It increases mitochondrial oxygen consumption and reduces ROS production in wild type but not SIRT3-KO cells.1 It reversed cardiac hypertrophy in mice1 and rescued myocardial and mitochondrial energetics in type 2 diabetic rats2. It was shown to increase SIRT3 expression in the hippocampus and attenuated surgery-induced memory loss, neuronal apoptosis, neuroinflammation and oxidative damage.3 It increases expression of adipocyte gene markers, gene-involved lipolysis and glucose transport and in general, promotes insulin sensitivity.4
Conjugation
Unconjugated
Buffer
Beige solid
Storage Conditions
-20°C

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