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Vandetanib

CAT: 0498-bs-83268C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83268C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A potent and selective inhibitor of VEGFR2, (KDR IC50 = 40 nM) . Also inhibits fms-like tyrosine kinase 4 (VEGFR3, IC50 = 110 nM) and epidermal growth factor receptor (EGFR/HER1, IC50 = 500 nM) but shows selectivity against a panel of other tyrosine and serine-threonine kinases. Inhibits colony formation in seven cancer cell lines2. Displays anti-angiogenesis activity3.
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
-20°C

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