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Olaparib

CAT: 0498-bs-83259C-01Size: 10 mM/1 mL DMSODry Ice: NoHazardous: No
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CAT#:0498-bs-83259C-01Size:10 mM/1 mL DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A highly potent and selective PARP-inhibitor with IC₅₀ values of 5 nM and 1 nM for PARP-1 and PARP-2, respectively.1 In a genetically engineered mouse model for BRCA1-associated breast cancer olaparib inhibited tumor growth and improved survival with no signs of toxicity.2 Synergizes with many other anticancer agents.3 Shows efficacy in colorectal cancers.4 Prevents house dust mite allergen-induced asthma in a mouse model.5
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

Alternative Products

CatalogName
WGC308113-10mgOlaparib

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