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Entacapone

CAT: 0498-bs-83225C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83225C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent catechol O-methyltransferase (COMT) inhibitor (IC50 = 14.3, 20.1 and 73.3 nM for rat liver soluble COMT, total COMT and membrane-bound COMT respectively) .1 Increases bioavailability of L-DOPA as adjunct therapy for Parkinson's disease.2 Inhibits α-synuclein aggregation in vitro and inhibits α-synuclein-induced cell death in PC-12 cells3. Antioxidant. Inhibits oxidative stress-induced cell death4.
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

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