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AdipoRon

CAT: 0498-bs-83216C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83216C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A novel potent and selective adiponectin (AdipoR1 and AdipoR2) receptor agonist, Kd=1.8 and 3.1 μM respectively1. Displayed similar effects to adiponectin in muscle and liver such as activation of PPARα and AMPK signaling pathways. It also reversed insulin resistance and glucose intolerance in mice on a high-fat diet. It ameliorated diabetes in a genetically obese mouse model and prolonged the shortened lifespan of db/db mice on a high-fat diet1. Active in vivo.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
RT

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