5-Azacytidine

CAT: 498-bs-83175C-01Size: 10 mM/1 mL DMSODry Ice: NoHazardous: No
10 mM/1 mL DMSOSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Specific inhibitor of DNA methyltransferase1. Incorporates into DNA and covalently reacts with and inhibits DNA methyltransferases. Induces demethylation and reactivation of silenced genes2. Increases stem cell reprogramming efficiency3. Induces cardiac differentiation of human mesenchymal stem cells by activating ERK4. Induces apoptosis in multiple myeloma cells via ATR-mediated DNA double strand breaks5. Cell permeable.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C