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Ketoconazole (base)

CAT: 0498-bs-83136C-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83136C-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Ketoconazole is a broad spectrum antifungal agent which acts via inhibition of a cytochrome P450, CYP51A1 which is a lanosterol 14-demethylase.1 Also inhibits CYP3A and CYP1A1.2 Inhibits adrenal steroidogenesis.3 Downregulates cholesterol synthesis in drug-tolerant human lung cancer cell lines.4 Blocks the biosynthesis of leukotrienes (LT) via inhibition of 5-lipoxygenase and dose dependently inhibits LT-mediated bronchoconstriction in guinea pigs.5
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
RT

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B1240-10(+)-Ketoconazole
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HY-B0105A-01(+) -Ketoconazole
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