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GW788388

CAT: 0498-bs-83131C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83131C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent inhibitor of TGF-β receptor kinases ALK4, ALK5 (IC50=18 nM), ALK7, and TGFβRII, but not BMP type II receptor kinase.1,2 Blocks TGF-β-mediated signaling, including collagen type I and VEGF, in turn reducing fibrosis and angiogenesis in various mouse models.3,4 GW788388 attenuates TGF-β-induced epithelial to mesenchymal transition (EMT) in human peritoneal mesothelial cells.5
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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CatalogName
A8301-5.1GW788388

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