Products for Research Use Only

AM-580

CAT: 0498-bs-83129C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83129C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Retinoic acid analog acting as a RARα agonist (Kd = 8 nM) .1 Induces or blocks differentiation depending on cell type and environment.2,3 In combination with CHIR-99021 it induces differentiation of human induced pluripotent stem cells (iPSCs) into intermediate mesoderm (80% induction rate in 5 days) capable of forming kidney structures.4 AM-580 exhibits anti-angiogenic activity in vivo, and induces differentiation of acute promyelocytic leukemia cells.5,6
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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