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Metolazone

CAT: 0498-bs-83120C-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83120C-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Activates mitochondrial unfolded protein response (UPRMT) and -increases C. elegans lifespan.4 Clinically useful diuretic that inhibits the thiazide-sensitive Na+-Cl– cotransporter (NCC) (IC50 = 0.3 µM rat), blocking sodium reabsorption.2,3 Metolazone also inhibits human carbonic anhydrase isoforms VII, XII, and XIII with nanomolar potency.4.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
RT