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CID1067700

CAT: 0498-bs-83118C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83118C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A specific competitive inhibitor of nucleotide binding to Rab7, an endosome-localized small GTPase.1 It interferes with the Rab7-RILP interaction, locking the GTPase in an inactive conformation.2 Impairs B cell class switching and plasma cell survival dampening, the pathogenic autoantibody response in lupus.3 Inhibits the Arf-like small GTPase Arl8b, blocking cellular egress of b-coronaviruses (SARS-CoV-2) which utilize a lysosomal exocytosis pathway.4
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

Alternative Products

CatalogName
abx283153-01CID1067700
TBI5401-5MGCID1067700, Rab7 GTPase inhibitor

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