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Isohelenin

CAT: 0498-bs-83116C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83116C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A sesquiterpene lactone isolated from Mexican Indian medicinal plants known to have anti-inflammatory properties. A potent inhibitor of NFB (complete inhibition at 5 M) 1 acting via inhibition of IKK6. Isohelenin-mediated NFB inhibition suppresses IL-8 expression2, iNOS expression3 and RANTES biosynthesis4. Displays protective effects in endotoxic shock in rodent models.5 Induces apoptosis in glioma cells.6
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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