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Locostatin

CAT: 0498-bs-83112C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83112C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Inhibits cell migration by disrupting the interaction between Raf kinase inhibitor protein (RKIP) and Raf-1 kinase.1 Locostatin covalently binds to His86 of RKIP and also disrupts its interaction with G protein-coupled receptor kinase 2.2 Effectively inhibits cytokine release by human lymphocytes.3 Alleviates CCl4-induced liver fibrosis in a mouse model.4 A useful probe to explore the complex functions of RKIP in cell physiology.5
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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