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Deferasirox

CAT: 0498-bs-83066C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83066C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Clinically useful iron chelator used in long term care of ß-thalassemia and other heavily transfused hematological patients.1,2 It has been shown to potent inhibitor of JumonjiC Domain-Containing Histone Demethylases (IC50’s = KDM4A (JMJD2A) 4.76 µM, KDM5A (JARID1A) 5.00 µM, KDM6B (JMJD3) 3.95 µM) .3 Deferasirox has also been investigated as a potential anticancer agent.4-6
Conjugation
Unconjugated
Buffer
Off-white to white solid
Storage Conditions
-20°C

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