SR-717

CAT: 0498-bs-83048C-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0498-bs-83048C-01Size:10 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cell permeable and exceptionally selective STING agonist (IC50 = 7.8 µM) . It displayed robust antitumor activity in B16.F10 melanoma and MC38 colorectal adenocarcinoma mouse models. SR-717 promoted the activation of CD8+ T, natural killer, and dendritic cells as well as promoting antigen cross-priming. It was able to induce PD-L1 expression in THP1 cells and in primary human PBMC’s.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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